Published on Thursday, the Times Higher Education (THE) group's European Universities Top 200 list is based on its world rankings released in October last year, in which ETH Zurich placed ninth.
The European list is dominated by British universities, which clinched nearly a quarter of places (46) including seven in the top ten.
ETH Zurich was the top non-UK university in the list, placing fourth after Oxford, Cambridge and Imperial College London.
Speaking to The Local, Lino Guzzella, President of ETH Zurich, said he was proud of the university's ranking.
“We believe that our outstanding students and our international faculty are the main reasons for this result. Peer recognition is both confirmation and encouragement to continue on our way.”
In a statement, THE said Switzerland was one of several strong performers relative to population size, with a total of nine institutions in the top 200.
ETH Zurich's sister school EPFL in Lausanne placed 11th, with the universities of Basel, Zurich, Bern, Geneva, Lausanne, Fribourg and St Gallen all making the list.
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THE editor Phil Baty said that while British universities remained at the top of the rankings, the UK faced tough competition from other European nations which could lead to a “major shake-up in the international student recruitment market”.
"While the market leader, the UK, shoots itself in the foot and faces losing market share over restrictive study and work visa policies, anti-immigration rhetoric and prohibitively high tuition fees, other European countries are poised to capitalize and take more and more of the UK's share of students," said Baty.