The six-kilometre trip will typically set you back £22.83 (around 33 Swiss francs), while the round trip costs nearly £46, No. 1 Currency said.
That amounts to £3.80 per kilometre, more than 20 times the rate for a similar trip between Istanbul and its airport, the company said.
Copenhagen comes a close second as the place with the most expensive airport-city transfer where the eight-kilometre trip costs £2.99 per kilometre, according to the ranking.
Brussels ranks as the third most costly (£2.47 per kilometre), followed by London-Heathrow (£2.43).
But if you pay through the nose for a cab in Geneva, one advantage is that its airport is nearby.
(Passengers arriving at Geneva airport also have the alternative of free public transit - bus or train - on the Unireso network for up to 80 minutes, with free tickets dispensed near luggage carousels.)
By comparison, the 28-kilometre distance from Heathrow airport to London city centre means you have to cough up an “eye-watering” £68, an amount that rises to £136 for the round trip.
On a per kilometre basis, Istanbul ranks as the cheapest place to take a taxi from the airport at £0.19.
But the absolute cheapest cab ride between a European city centre and its nearest airport is in Sofia, Bulgaria, where the 10-kilometre trip will set you back just £3.33, No. 1 Currency said.
“Our research reveals that there is a huge variation in the cost of a taxi depending on which European city you’re visiting, so do your research before you travel,” Simon Phillips, retail director for No. 1 Currency said in a statement.
“If the airport to city centre taxi ride is particularly pricey, like Milan, then taking the bus or train may be the better option,” Phillips said.
(Malpensa airport is 50 kilometres from Milan’s centre, with average cabs costing £58.59 for the one-way trip).
“Alternatively, you could book a taxi in advance of travelling to your weekend destination, as this could work out significantly cheaper than flagging down a taxi outside the airport.”
No. 1 Currency is part of FEXCO, a multinational financial and business solutions provider, with operations in 28 countries worldwide.
It bills itself as a leading provider of foreign exchange services in the UK.