The fire broke out at 5.30am in a building storing antiques and liquidated goods, according to Thurgau cantonal police.
“A building has collapsed. The flames have now spread to two others,” said spokesman Matthias Graf.
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Over 100 firefighters were fighting the blaze with the help of two army helicopters.
One Super-Puma employed to collect water from nearby Bodensee (Lake Constance) dispatched 4,000 litres per journey to the site of the fire.