Over 140 million Swiss francs ($140 million/128 million euro) has been invested over the past three years in the museum dedicated to the world's most popular sport.
"We couldn't ignore the turbulence, it was not easy," said managing director Stefan
Jost of the work which continued against the backdrop of the current scandal engulfing the sport's governing body.
"But we had to focus on our mission, to build a museum and a team."
Blatter along with Uefa chief Michel Platini have both been suspended from all football activity for eight years by a Fifa tribunal, over a two-million-franc ($2 million) payment that Blatter approved to the Frenchman.
"It's not a museum about personalities, it's about what football gives to people around the world," added Jost of the project, which was the brainchild of Blatter, who has headed Fifa since 1998.
"We don't know if the new president will participate in the inauguration," said Jost, adding that the interim secretary general Markus Kattner would be present.
In the centre of Zurich, and covering 3,000 square metres on three levels, the museum will exhibit objects retracing the history of football, with a library including 5,000 works.
"We started with just two objects in our collection, namely the original World Cup trophy and a jersey from the Italian world champion team of 1938," explained artistic director David Ausseil.
"The funds were then supplemented with donations, loans or acquisitions in auctions."
Fifa hopes that the museum will attract 250,000 visitors per year, comparable with the Olympic museum in Lausanne, which drew 300,000 in 2015.